
Biologics therapy is a minimally invasive solution designed to manage hip pain and injuries, offering benefits like tissue regeneration, reduced inflammation, and improved mobility. This protocol outlines a step-by-step approach for delivering intra-articular (joint) and intra-muscular (IM) stem cell treatments to treat conditions such as osteoarthritis, labral tears, and chronic hip pain.
Individuals with mild to moderate hip osteoarthritis.
Patients with labral tears, tendinopathy, or other soft tissue injuries.
Patients seeking alternatives to surgery or conventional pain management therapies.
Patients should be in generally good health, with no active infections or contraindicated conditions.
Infections or Inflammation: Active infections or inflammation at the injection site or surrounding areas.
Allergic Reactions: A history of severe allergies to injectables, exosome products, or anesthetics should be assessed.
Severe Degeneration: Advanced degenerative joint disease requiring surgical intervention.
Chronic Conditions: Patients with uncontrolled diabetes, blood clotting disorders, or severe autoimmune diseases should be carefully evaluated or excluded.
Sterile Environment: Ensure the treatment room is set up with sterile instruments and surfaces to prevent any contamination.
Required Equipment:
Biologics vial (check expiration date and manufacturer guidelines for storage and handling).
Ultrasound guidance tools.
3-5 mL syringes.
Topical antiseptic solution (e.g., chlorhexidine or alcohol) for skin preparation.
Anesthesia supplies if needed.
Informed Consent: Explain the procedure, expected benefits, risks, and aftercare. Address patient concerns.
Anesthesia Options: Offer local anesthesia for comfort. Allow sufficient time for effect (5-15 minutes for topical, 2-5 minutes for injectable).
Skin Preparation: Cleanse the hip area thoroughly with antiseptic to minimize infection risk.
Intra-Articular Therapy: Administered directly into the hip joint cavity for cartilage regeneration and pain relief.
Intra-Muscular Therapy: Targeted at soft tissue injuries such as tendinopathy or muscle tears around the hip.
Use ultrasound guidance to identify and mark precise injection points.
Draw the appropriate volume of stem cell product (e.g., 1–3 mL) into a sterile syringe.
For intra-articular treatments, insert the needle into the joint space under ultrasound guidance and inject slowly.
For intra-muscular treatments, deliver the stem cell solution directly into the affected muscles (e.g., gluteal or iliopsoas muscles).
Apply gentle pressure at the injection site post-procedure and monitor for immediate reactions.
Avoid weight-bearing activities and strenuous movements for 24–48 hours post-treatment.
Let the patient know that mild swelling, discomfort, or bruising may occur and typically resolves naturally.
Recommend acetaminophen for pain relief, avoiding NSAIDs to preserve the inflammatory healing phase.
Schedule a follow-up visit 2-4 weeks after the procedure to assess progress, recovery, and pain levels.
Instruct the patient to contact the clinic if they experience severe pain, significant swelling, or signs of infection (e.g., redness, warmth, fever).
Observe the patient for 5-10 minutes after the procedure to ensure no adverse reactions, particularly allergic reactions.
Keep epinephrine and antihistamines on hand in case of any unexpected allergic response.
Ensure that the clinical team is prepared to respond to emergencies, although such reactions are rare.
Use strict aseptic techniques throughout the procedure to minimize the risk of infection.
Assess patient outcomes during the first follow-up appointment, focusing on pain relief, joint mobility, and overall satisfaction.
Document any changes in symptoms and discuss whether additional sessions may be needed.
Encourage regular check-ins over the following 6-12 months to track improvements and address any further needs.
For optimal results, additional treatments may be spaced 4–6 weeks apart, depending on the patient’s response and clinical findings.
Record all relevant details in the patient’s medical record, including:
Type and dosage of product used.
Injection locations and techniques used.
Patient response during the procedure.
Document any post-treatment observations or instructions provided to the patient.
Include notes on patient feedback during follow-up appointments to monitor the treatment’s effectiveness over time.
Track any need for adjustment in dosing or frequency in the patient’s file.
Biologics therapy is an alternative treatment option for hip pain and injuries, providing a less invasive alternative to traditional approaches. By adhering to this structured protocol, medical professionals can ensure safe patient-centered care, helping individuals regain mobility and improve their quality of life.

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