Building better bodies, one cell at a time.

Orthopedic Conditions

Biologic therapies in orthopedics aim to enhance tissue regeneration, reduce inflammation, and restore function in musculoskeletal injuries and degenerative conditions.

Common Conditions Treated

  • Osteoarthritis: Degeneration of joint cartilage leading to pain and stiffness.
  • Meniscal Tears: Injuries to the knee’s cartilage.
  • Ligament Injuries: Such as ACL (anterior cruciate ligament) and MCL (medial collateral ligament) tears.
  • Tendinopathies (Tendon Pain): Chronic tendon injuries.
  • Rotator Cuff Injuries: Tears or inflammation in the shoulder tendons.
  • Fracture Non-Unions: Broken bones that fail to heal properly.

Treatment Modalities

  • Mesenchymal Stem Cell (MSC) Therapy: Utilizes high-quality MSCs from reputable laboratories to promote cartilage and bone regeneration.
  • Exosome Therapy: Employs MSC-derived exosomes to modulate inflammation and facilitate tissue repair.
  • Platelet-Rich Plasma (PRP): Concentrated platelets are injected to release growth factors that aid healing.

Procedure Overview

Patient Selection:

  • Inclusion Criteria: Patients with mild to moderate degenerative joint disease or soft tissue injuries.
  • Exclusion Criteria: Active infections, malignancies, or severe systemic diseases.

Preparation:

  • Informed Consent: Discuss potential benefits, risks, and alternative treatments.
  • Anesthesia: Local anesthesia at the injection site.
  • Aseptic Technique: Ensure a sterile environment to prevent infection.

Administration:

  • Injection: Under ultrasound guidance, inject the biologic agent into the affected area.

Post-Procedure Care:

  • Activity Modification: Advise limited weight-bearing activities for 48 hours.
  • Follow-Up: Monitor for adverse reactions and assess clinical improvement.

Supporting Studies

  • Mesenchymal Stem Cell-Derived Exosomes in Osteoporosis Treatment: This systematic review highlights the efficacy of MSC-derived exosomes in improving bone density and structure.
  • MSC-Derived Exosomes in Musculoskeletal Diseases: The study discusses the potential of MSC-derived exosomes in treating various musculoskeletal conditions. European Journal of Medical Research