Orthopedic Conditions
Biologic therapies in orthopedics aim to enhance tissue regeneration, reduce inflammation, and restore function in musculoskeletal injuries and degenerative conditions.
Common Conditions Treated
- Osteoarthritis: Degeneration of joint cartilage leading to pain and stiffness.
- Meniscal Tears: Injuries to the knee’s cartilage.
- Ligament Injuries: Such as ACL (anterior cruciate ligament) and MCL (medial collateral ligament) tears.
- Tendinopathies (Tendon Pain): Chronic tendon injuries.
- Rotator Cuff Injuries: Tears or inflammation in the shoulder tendons.
- Fracture Non-Unions: Broken bones that fail to heal properly.
Treatment Modalities
- Mesenchymal Stem Cell (MSC) Therapy: Utilizes high-quality MSCs from reputable laboratories to promote cartilage and bone regeneration.
- Exosome Therapy: Employs MSC-derived exosomes to modulate inflammation and facilitate tissue repair.
- Platelet-Rich Plasma (PRP): Concentrated platelets are injected to release growth factors that aid healing.
Procedure Overview
Patient Selection:
- Inclusion Criteria: Patients with mild to moderate degenerative joint disease or soft tissue injuries.
- Exclusion Criteria: Active infections, malignancies, or severe systemic diseases.
Preparation:
- Informed Consent: Discuss potential benefits, risks, and alternative treatments.
- Anesthesia: Local anesthesia at the injection site.
- Aseptic Technique: Ensure a sterile environment to prevent infection.
Administration:
- Injection: Under ultrasound guidance, inject the biologic agent into the affected area.
Post-Procedure Care:
- Activity Modification: Advise limited weight-bearing activities for 48 hours.
- Follow-Up: Monitor for adverse reactions and assess clinical improvement.
Supporting Studies
- Mesenchymal Stem Cell-Derived Exosomes in Osteoporosis Treatment: This systematic review highlights the efficacy of MSC-derived exosomes in improving bone density and structure.
- MSC-Derived Exosomes in Musculoskeletal Diseases: The study discusses the potential of MSC-derived exosomes in treating various musculoskeletal conditions. European Journal of Medical Research