Neurological Disorders
Biologic therapies aim to promote neuroregeneration, modulate neuroinflammation, and restore neural function in neurological disorders.
Common Conditions Treated
- Stroke: Interruption of blood supply to the brain.
- Traumatic Brain Injury: Damage to the brain from external force.
- Spinal Cord Injury: Damage leading to loss of function.
- Neurodegenerative Diseases: Such as Parkinson’s and Alzheimer’s.
- Multiple Sclerosis: Immune-mediated attack on the nervous system.
Treatment Modalities
- Mesenchymal Stem Cell (MSC) Therapy: Uses high-quality MSCs to replace damaged neurons and support neurogenesis (formation of new neurons).
- Exosome Therapy: Exosomes derived from MSCs deliver neuroprotective agents and modulate immune responses.
Procedure Overview
Patient Selection:
- Inclusion Criteria: Patients with acute or chronic neurological deficits.
- Exclusion Criteria: Active central nervous system infections or malignancies.
Preparation:
- Informed Consent: Discuss the experimental nature, potential benefits, and risks.
- Imaging: Obtain MRI or CT scans to identify target areas.
Administration:
- Intrathecal Injection: Deliver biologic agents into the cerebrospinal fluid.
- Intravenous Infusion: Systemic delivery for widespread neuroprotection.
Post-Procedure Care:
- Monitoring: Observe for neurological changes or adverse effects.
- Rehabilitation: Implement physical and occupational therapy as needed.
Supporting Studies
- Neural Stem Cell-Derived Exosomes in Neuroregeneration: This review explores the role of exosomes in neural repair and their therapeutic potential. Stem Cell Research
- MSC-Derived Exosomes in Neurological Disorders: The study discusses the application of MSC-derived exosomes in treating neurological conditions. Biolres