Lung Diseases
Biologic therapies in lung diseases focus on reducing inflammation, repairing damaged lung tissue, and improving oxygen exchange. By enhancing mitochondrial function and cellular regeneration, these treatments target chronic and progressive respiratory conditions.
Common Conditions Treated
- Chronic Obstructive Pulmonary Disease (COPD): Chronic inflammation causing airflow limitation.
- Pulmonary Fibrosis: Scarring of lung tissue leading to reduced elasticity.
- Asthma: Chronic airway inflammation resulting in breathing difficulties.
- Acute Respiratory Distress Syndrome (ARDS): Severe inflammation and fluid buildup in the lungs.
- Lung Damage Post-COVID-19: Residual lung scarring and inflammation from COVID-19.
Role of Stem Cells and Mitochondria
- Stem cells restore lung tissue by reducing inflammation and promoting repair of alveoli (air sacs). Their exosomes improve mitochondrial function, which is crucial for energy production and efficient oxygen exchange.
Treatment Modalities
- Mesenchymal Stem Cell (MSC) Therapy: High-quality MSCs repair damaged lung tissues and modulate inflammation.
- Exosome Therapy: Reduces inflammatory cytokines and enhances tissue regeneration.
- IV Infusion of Biologics: Delivers systemic support for widespread lung conditions.
Procedure Overview
Patient Selection:
- Ideal Candidates: Individuals with chronic respiratory diseases or post-viral lung damage.
- Contraindications: Active respiratory infections or advanced lung failure requiring immediate mechanical support.
Preparation:
- Pulmonary Function Tests (PFTs): Assess baseline lung capacity and function.
- Imaging: Chest X-rays or CT scans to evaluate lung structure.
Administration:
- IV Infusion: Delivers biologics to modulate systemic and localized lung inflammation.
- Nebulized Biologics (Experimental): Inhalation therapy for direct lung delivery.
Post-Treatment Care:
- Recommend pulmonary rehabilitation and breathing exercises.
- Regular follow-ups to monitor lung function improvement.
Supporting Studies
- MSC Therapy for Pulmonary Fibrosis: Highlights stem cell efficacy in reducing scarring and inflammation. Read study
- Exosomes in Respiratory Diseases: Discusses the therapeutic role of exosomes in lung repair. Read study